Should Compounding Pharmacies Join a GPO? The Pros and Cons of Group Purchasing

Mar 13, 2025

Compounding pharmacies can save money and simplify operations by joining a Group Purchasing Organization (GPO). GPOs negotiate bulk discounts, reduce administrative costs, and improve supply chain management. But is it the right choice for your pharmacy? Here's a quick breakdown:

Key Benefits of GPOs:

  • Financial Savings: 10-18% cost reductions on average.

  • Streamlined Operations: Pre-negotiated contracts, cloud-based inventory tools, and simplified purchasing.

  • Regulatory Support: Assistance with compliance and quality standards.

  • Market Leverage: Increased buying power through collective membership.

Potential Downsides:

  • Less Flexibility: Standardized contracts may limit customization.

  • Membership Costs: Some GPOs charge fees or require minimum purchases.

  • Dependency: Relying on GPOs could reduce direct supplier relationships.

Independent Purchasing:

  • Pros: Full control over supplier choices and order customization.

  • Cons: Higher costs, more administrative work, and limited negotiation power.

Quick Comparison Table:

Aspect

GPO Membership

Independent Purchasing

Cost Savings

10-18% average savings

Higher costs overall

Flexibility

Limited by GPO contracts

Fully customizable

Administrative Work

Reduced

Increased

Compliance Support

Provided by GPO

Self-managed

Bottom Line: GPOs are ideal for cost savings and operational efficiency, while independent purchasing offers more flexibility and control. Evaluate your pharmacy’s needs, purchasing patterns, and compliance requirements to decide the best fit.

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1. Benefits of GPO Membership

Joining a Group Purchasing Organization (GPO) can help compounding pharmacies save money and simplify operations. According to CMS data, GPOs are expected to save the healthcare industry $456.6 billion between 2017 and 2026, highlighting their financial impact.

Financial Advantages: By leveraging collective purchasing power, GPOs negotiate better prices through bulk discounts. Member pharmacies often benefit from:

  • Up-front pricing discounts

  • Reduced administrative costs

  • Savings through standardized product options

In addition to these immediate savings, GPOs improve procurement processes with better supply chain management.

Supply Chain Improvements: GPOs offer cloud-based tools that make supply chain management more efficient for compounding pharmacies. Here's how:

Category

Features

Impact

Inventory Management

Cloud tracking, auto-reordering

Avoids stock shortages or excess stock

Order Processing

Centralized ordering system

Cuts down on time and errors

Quality Control

Verified supplier networks

Ensures reliable product quality

Expense Tracking

Analytics and forecasting tools

Supports smarter purchasing decisions

These tools, backed by digital tracking and analytics, ensure a smooth and efficient supply chain process.

Transparent Cost Structure: Modern GPOs prioritize clarity in their fee structures:

  • Some GPOs offer free memberships, earning revenue through supplier fees.

  • Administrative fees are disclosed annually.

  • Any fees above 3% must be contractually outlined.

For both 503A and 503B pharmacies, streamlined supply chain management ensures consistent access to essential materials while maintaining strict quality standards.

2. Operating Without a GPO

Choosing independent purchasing gives compounding pharmacies full control over their supply chain but requires careful resource management. While GPOs simplify the process, going solo allows for a more tailored approach that some facilities prefer.

Direct Supplier Management

Independent purchasing means managing supplier relationships directly, which requires more effort but allows for greater customization. Pharmacies can:

  • Adjust orders to match their exact needs

  • Negotiate terms directly with manufacturers

  • Select specific products

  • Gain complete transparency in their supply chain

However, this approach takes time and procurement expertise to ensure compliance and maintain quality standards.

Cost Considerations

Operating independently often leads to higher costs and administrative work:

Cost Factor

Impact

Management Strategy

Purchasing Power

Smaller order volumes result in higher costs

Strategic inventory planning

Administrative Costs

More staff time needed for procurement tasks

Streamlined ordering processes

DIR Fees

Payments tied to performance metrics

Focus on quality improvements

Generic Drug Margins

Lower profit margins due to competition

Broaden revenue streams

A survey found 63% of independent pharmacists see DIR fees as their biggest challenge. These financial hurdles highlight the importance of strong internal controls to meet compliance standards.

Regulatory Compliance

To navigate financial pressures, 503A and 503B facilities must maintain solid USP <797> compliance systems.

  • Quality Control Programs: Pharmacies need monitoring systems for environmental conditions, cleaning protocols, and staff training.

  • Documentation Management: Accurate records are critical, including:

    • Master Formulation Records

    • Compounding Records

    • Personnel training files

    • Quality assurance documents

"USP <797> forms the foundation for regulatory agencies, particularly state-level boards of pharmacy, to address unsafe compounding practices in pharmacies." - Wolters Kluwer

Supply Chain Visibility

Independent purchasing also ensures full transparency in sourcing and quality control. Pharmacies can:

  • Trace product origins

  • Verify ethical sourcing

  • Anticipate and manage risks

  • Maintain direct oversight of product quality

Though managing procurement without a GPO requires more resources, it offers the flexibility and control that can be essential for meeting specific operational needs.

Direct Comparison: GPO vs. Independent Purchasing

Compounding pharmacies face key differences when choosing between GPO membership and independent purchasing. Here's how they stack up:

Financial Impact

The financial differences between these two approaches are clear:

Aspect

GPO Membership

Independent Purchasing

Annual Savings

Average $50,000 with programs like Pharmacy Select

Higher costs overall

Negotiation Power

10-18% savings on average compared to direct purchases

Limited ability to negotiate

Generic Drug Pricing

Bulk pricing offers lower costs

Higher per-unit expenses

Administrative Costs

Saves time for procurement staff

Requires more staff resources

These numbers highlight the cost advantages of GPO membership, making it a strong consideration for pharmacies aiming to cut expenses.

Supply Chain Management

The procurement method directly affects how pharmacies handle supplier relationships and logistics:

Factor

GPO Model

Independent Model

Supplier Access

Contracts with multiple vendors already negotiated

Direct relationships with manufacturers

Order Flexibility

Standardized ordering processes

Customizable orders

Contract Terms

Fixed through GPO agreements

Can be negotiated individually

Supply Chain Visibility

Managed via GPO systems

Direct tracking and oversight

Operational Considerations

GPO membership simplifies many processes but comes with pre-set contract terms that may reduce day-to-day flexibility.

Dan Fuchs of Dick's Pharmacy explains:

"If you're in the pharmacy business, you have to join a buying group or else you're just not going to make it. So, you might as well join the best one out there and I feel IPC is the best one out there."

Compliance and Oversight

Regulatory compliance is handled differently depending on the purchasing model:

Compliance Aspect

GPO Approach

Independent Approach

Vendor Vetting

Vendors are pre-vetted through the GPO

Pharmacies must verify vendors themselves

Fee Disclosure

Annual disclosure of administrative fees

Direct cost tracking required

Quality Assurance

Standardized across the GPO network

Managed individually by the pharmacy

Risk Management

Shared responsibility with the GPO

Fully self-managed by the pharmacy

Market Position

Smaller compounding pharmacies often face challenges in staying competitive. GPO membership helps level the playing field. Danny Cottrell, RPh, of Medical Center Pharmacy, shares:

"Without them to do some negotiations for you on generic prices you would just be twisting in the wind. I don't see how a guy can be open without being in one."

Hybrid Solutions

A hybrid approach combines the benefits of GPO membership with the flexibility of independent purchasing. Pharmacies using this strategy can:

  • Take advantage of GPO pricing for high-demand items

  • Keep direct supplier relationships for specialized needs

  • Improve inventory management

  • Balance cost savings with operational control

Ultimately, the choice between GPO membership and independent purchasing depends on a pharmacy's specific needs, order volume, and operational goals.

Making Your Decision

Now that we've covered the pros and cons, here's a step-by-step guide to help you decide if joining a GPO is right for your pharmacy:

Step 1: Review Annual Purchasing Patterns

Take a close look at your pharmacy's purchasing habits. Here's a quick breakdown:

Category

What to Evaluate

High-Volume Items

Monitor monthly usage and expenses

Specialty Products

Identify unique sourcing needs

Emergency Supplies

Check how often you run out

Bulk Purchases

Assess your available storage space

Step 2: Calculate Potential Savings

Look at both direct and indirect costs. GPO membership can lower expenses on purchases while also cutting down on administrative work and simplifying procurement processes.

Step 3: Evaluate Regulatory Impact

Consider how partnering with a GPO might affect your compliance and risk management efforts.

"The quality, safety, and appropriateness of the preparations remains the fiduciary responsibility of the dispensing pharmacy and pharmacist. This duty is not transferable."

Step 4: Assess Operational Effects

Think about how a GPO partnership could change your daily operations. Here are some key points:

Aspect

What to Consider

System Integration

How it fits with ordering and inventory workflows

Staff Training

Time needed to learn new processes

Quality Control

How vendors are vetted and monitored

Step 5: Determine Flexibility Needs

Decide if a mixed strategy works better for your pharmacy. For example:

  • Use GPO contracts for standard supplies while keeping relationships with specialty vendors.

  • Take advantage of GPO analytics tools to guide purchasing decisions.

  • Join regional purchasing committees for additional input.

Step 6: Review Contract Terms

Carefully examine the details of any GPO contract, including:

  • Membership fees and how payments are structured.

  • The length of the contract and termination policies.

  • Minimum purchase commitments.

  • Reporting requirements.

  • How much freedom you have in selecting vendors.

For more resources, check out 503Pharma's educational platform.

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© 2025. All rights reserved. 503Pharma

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Insights to elevate compounding pharmacy practice and business

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© 2025. All rights reserved. 503Pharma

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